The aim of the NEUROWEB project is to design and develop an intelligent web-based system that allows integration, easy access and sharing of clinical data and biomedical knowledge, with a prototypical application in neurology and neurosciences: the system will support scientists and doctors in they every day work by allowing them define workflows that can be stored, shared and executed any time. NEUROWEB project represents one of the first applied research financed by EU e-Health programme, in the field of neurovascular diseases that might systematically generalise the exploitation of genomic information into the daily clinical practise, facilitating significant quality improvements in diagnosis and therapy. The Neuroweb project is focused on the cerebrovascular diseases defined by the WHO in diagnostic 433, 434 and 435.