With the diffusion of ICT systems in medicine, today it’ s possible to connect together many health structures (hospitals, outpatients, clinic, GPS, etc.) located in various worldwide countries. In this way it is possible to create a network to access easier and quickly to medical information in order to obtain clinical consultations, epidemiological studies, biomedical knowledge by all health operators (physicians, technicians, researchers, etc.). This is useful to obtain results from research and innovative methods of prevention and care and advanced clinical practices. So, thanks to the spread of intra/extra networks in healthcare, it is possible to distribute knowledge and information useful to health operators and to patients/citizens in the globalized context. Through this interchange of data streams it is also possible to identify, analyzing some statistical and epidemiological data, pathologies such as the infective ones that torment developing countries and in particular the ones of Africa where, whole generation of peoples, especially children, are affected. The year 2007 has been declared the year of science and technology for Africa with the target to increase and improve international cooperation in scientific and technological field. For us the collaboration in telemedicine and e-health activities must be developed to strengthen data communication between clinical and health structures in Italy and the ones of many zones in Africa. In the difficult international scenario, dotted by large differences between countries of different continents and in particular of Africa, telemedicine and e-Health can have an important role for peoples, in a sector like that of combating diseases and can contribute to solve dramatic health problems that afflict the continent. Telemedicine fails and can not solve the structural problems that these countries have – water and hunger for example – but it can allow easy access to information seeking to limit the gap that is mainly in health, especially in diagnostic equipment and drug therapies. The introduction of ICT in African health sector can help to overcome the so-called "digital divide" that the technological gap in informatics and information that, perhaps, more than in other areas, affects and inhibits the development. Already today there are many projects aiming to develop systems and telemedicine services between Italian and health structures (hospitals, laboratories, local and regional districts, etc.) of many African countries.healthcare services, allowing the so called “ Continuity of care” .